Using her Aspire S7 Ultrabook, Fox leads a group of scientists to develop software that can translate the sounds that dolphins make.
The work follows the Kiefer Sutherland-fronted spot earlier this year.
Fox said: "I decided to work with Acer because I really like computers – the more high-tech, the better. The campaign was fun and it gave me an opportunity to show a different side of myself."
The work is running in the UK, the US, Russia, Germany, France and China. It was directed by Ivan Zacharias through Stink. Post-production was by The Mill.