It is understood that Brent, who joined the firm in 2005, has taken a global marketing role within the organisation, but no one at Boots would comment on the restructure.
Fagan joined Boots Opticians last September from DSG International (DSGi). She took over responsibility for running more than 280 Boots Opticians stores and replaced Chas McShane, who retired after a year in the job.
During her time at DSGi, Fagan was marketing director then managing director of The Link. In 2006, she became group media director overseeing DSGi's contracts with its ad and media agencies across its retail brands.
Brent was responsible for launching the 'Change one thing' healthy-living initiative last year, under which the retailer offered general health advice in-store. This was supplemented by Boots' first campaign promoting its 'Ask your Boots Pharmacy Team', which flagged up the 15,000 healthcare experts it employs at its stores.