The agency won the business after a final pitch against Adam & Eve/DDB and VCCP in a process handled by Oystercatchers.
Center Parcs previously worked with Beattie McGuinness Bungay, which won the business in 2010. Last year, it appointed 18 Feet & Rising to work on a strategy brief for the brand ahead of the creative pitch.
Brothers and Sisters will develop a communications platform to support Center Parcs’ growth strategy by attracting new consumers to the brand. In spring 2014, the fifth Center Parcs village, a £250m investment, will open at Woburn Forest, in Bedfordshire.
The new campaign will include TV, online content and digital marketing, print, outdoor, social media and internal communications.
Helen Horner, the head of brand at Center Parcs, said: "The launch of the fifth Center Parcs will be the biggest in our history. We need an agency that shares our passion for what we do and can deliver big, emotional creative ideas and a truly integrated campaign."
Andy Fowler, the executive creative director at Brothers and Sisters, said: "From the first meeting, Center Parcs felt like a good fit, their creative ambition, their understanding of digital innovation and their love for their brand, all stood out."