The ad agency will work initially on a new campaign for Fuller’s flagship ale brand, London Pride, after winning a competitive pitch against Isobel and Now.
UM London, which also won after a pitch, replaces MEC on the media account.
The Corner’s appointment ends a 15-year relationship between Fuller’s, which also owns a chain of pubs and beer brands including ESB and Discovery, and Doner.
Along with MEC, Doner took the decision not to repitch for the account.
Ian Bray, the managing director of Fuller’s, said: "We look forward to working with The Corner. We have been impressed by their energy and creativity throughout the pitch process and look forward to developing memorable work with them."