The campaign, created by Knifedge and backed by the Financial Times, allows companies to buy specially created video e-cards from Crisis to send in place of traditional company Christmas cards.
Those businesses that use the digital platform will be publicly thanked in ads running in the Financial Times.
The videos, filmed by Knifedge, feature eight people who have been helped by the charity singing Christmas songs. Each of the different executions end with the strapline: "With a little support, we can all be someone special."
Crisis chief executive, Leslie Morphy, said: "The Crisis Christmas Card features real people who have been helped out of homelessness by Crisis.
"We hope that companies will find them moving and authentic and choose these e-cards to replace their usual paper Christmas card mailings.
"Not only will the money raised help us transform the lives of more homeless people, but there are also environment benefits as they are entirely digital."
The charity claims that homelessness is on the rise due to the economic downturn combined with a severe housing shortage and austerity measures. Last year, 5,678 people slept rough, a 43% increase on the previous year.Follow @loullamae_es