The campaign, created by Ogilvy & Mather, forms part of a £1.6m drive and breaks on TV, supported by an on-pack promotion and in-store activity.
The ads will carry the strapline, "Together we can make a difference. Dove brings self-esteem education to girls".
Ali Fisher, brand manager of Dove Skin, Unilever UK, said the brand hoped to create a "step change" with the new campaign.
She said: "At Dove, we are passionate about our social mission and want to continue our support to help young girls and women develop a positive relationship with their bodies."
The 2012 Dove self-esteem programme aims to tackle women and girls' attitudes towards themselves, following research released by SIG, which showed 53% of girls in the UK have avoided certain activities because they feel bad about their looks.
The research also found that 22% of girls won't go to the beach or pool, while 20% have avoided physical activity or exercise, and one in 10 will not go to the doctor.
Dove's self-esteem programme has previously run in schools, engaging with more than 800,000 people in the UK, and has invested £250,000 to run one-hour workshops in partnership with the Beat Eating Disorders Association.
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