CHI & Partners created the TV and cinema ad, called "strobe", which launches in Asia, the US and the Middle East this week and will air in the UK later in the year.
In the spot, a series of stuntmen in LED suits are shown lighting up, one after another, giving the impression of a single figure moving across the Kuala Lumpur skyline.
The campaign aims to move Lexus beyond being known for its engineering and give the brand an imaginative and adventurous personality.
The work was written and art directed by Colin Smith and Angus Vine, and directed by Adam Berg through Stink. ZenithOptimedia will handle the media planning and buying in the UK.
Other spots in the 'Amazing In Motion' campaign include "steps" and "swarm". The latter featured a swarm of quadcopters and won a bronze Film Craft Lion at Cannes earlier this year.