The digital work will include managing Seat’s website, banner and social media. DLKW Lowe will also adapt Seat’s global outdoor, press and TV work.
Lowe and Partners was awarded the international Seat account in 2013. It is led by Lola, a Lowe and Partners agency in Barcelona, and works with other Lowe offices.
Chris Stevens, head of marketing at Seat UK, said Lowe Profero was selected for its "focus and expertise in strategic digital communications, as part of the wider communications mix".
Lowe Profero has also partnered with DLKW Lowe to work on brands such as Persil, British Heart Foundation and Tresemmé.
Dale Gall, the chief executive for Lowe Profero UK, said: "It’s great to be part of growing the Lowe and Partners global integrated offering.
"Seat has a great brand and it is an honour to apply Lowe Profero’s unique skills in creating and amplifying digital experiences to lead the integrated team."
Seat appointed Proximity London to handle its CRM account earlier this month.