The exhibition, which opens in the London gallery on January 31 and runs until February 18, will showcase photograph from David McCullin, David Bailey, Eve Arnold, Snowdon, Sam Taylor-Wood, Terry O'Neil and Stuart Franklin.
The exhibition will also highlight contributions from writers including Martin Amis, Ian Flemming, and Jilly Cooper, whose work has appeared in the News International-owned magazine, which is published with The Sunday Times.
The February 5 special anniversary issue of The Sunday Times Magazine will include the 50 "greatest" front covers.
Sarah Baxter, editor of The Sunday Times Magazines, said: "We're still here and producing the most exciting journalism and photography in the business."
Entrance to the exhibition is free.
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