The campaign, which was created by Walsh Trott Chick Smith, is designed to boost awareness of the helpline. Posters will be placed in all accident and emergency waiting rooms and doctors' surgeries from 6 December.
The poster has been designed to be as simple as possible to stand out from the other messages that clutter A&E departments' notice boards. The model featured in the poster was made by John Steed and shot by the photographer Piet Johnson.
Maggie Alexander, the director of the Brain and Spine Foundation, said: "Many of the people using A&E departments will have a brain or spine injury.
They and their families will be coping with a rapidly changing and sometimes frightening situation, a myriad of tests and a bewildering array of medical information.
"Our researchers found that the use of the phone cable to construct the brain and spine image drew people into the poster and was particularly attractive to young people, who are the group most likely to be affected by traumatic injury."
Three million people in the UK are affected by neurological conditions, but the Brain and Spine Foundation believes that because of the complexities of these conditions and the lack of NHS neuro specialists, they don't get the treatment and support they need. The helpline is staffed by qualified neurological specialists who can help patients and their families gain access to information.
The poster was written by Rob DeCleyn and art directed by Simon Micheli.