Frank will be tasked with overseeing all international campaigns for the film distributor, which is working on future releases including 'Harry Potter and the Deathly Hallows: Part 1' and 'Yogi Bear', as well as the strategic development and execution of regional and local campaigns.
She is currently managing director and senior vice president at ESPN EMEA. She led the launch of ESPN in the UK in 2009, which is regarded as a major milestone in the company's history.
Frank will relocate from London to Warner Bros Pictures' worldwide headquarters in Burbank, California this October, where she will report to Sue Kroll, Warner Bros Pictures' president of worldwide marketing.
Prior to her tenure at ESPN, Frank spent 12 years within Time Warner, working her way up from finance director for Turner Pictures and Cartoon Network through various roles to managing director and executive vice president, European Entertainment Networks, at Turner Broadcasting System Europe.
Kroll said: "I have known Lynne for many years and am thrilled that she will be taking on this key new role at the studio.
"When she worked with me at Turner, her expertise in opening new markets and localising global properties was a tremendous asset, as it will be here at Warner Bros as our business continues to evolve in the rapidly changing international marketplace."