The account, which includes the Goodfella’s pizza and Fox’s biscuit brands, has been handled by MediaCom since 2009.
Before that, the business was held by the Publicis Groupe-owned Equinox.
The review process follows a rumoured dispute over remuneration. MediaCom is believed to have resigned the business, but declined to comment.
2 Sisters manufactures meat products, ready-made meals and frozen foods for retailers such as Marks & Spencer, as well as under its own brands.
The company took on Goodfella’s and Fox’s, among other brands, when it acquired Northern Foods three years ago.
This article was first published on campaignlive.co.uk