Agencies have been asked to put themselves forward for different specialisms, including digital marketing, website build, apps and content.
It is understood that Leo Burnett, which handles creative work for the children’s charity, would be unaffected if the talks progress to a formal pitch.
OMD UK retained the NSPCC’s £10m media planning and buying business earlier this year after a competitive pitch. The agency will work on the account until at least 2019.
Last month, the NSPCC launched a two-minute animated film, created by Aardman and featuring dinosaurs, as part of a campaign encouraging parents to talk to their children about sexual abuse.
In a five-year strategy, the charity has set itself five goals: to help make children safer online, to prevent child abuse, to prevent child sexual abuse, to help children speak out about abuse and to help children get back on track if they have been abused.