The idea governing the overall campaign, which is comprised of six executions, is to get the public to "think bigger" and confront their prejudices about homeless people and consider the role The Big Issue Foundation plays in tackling it.
Each of the executions, created by TBWA/London, uses shots of the streets of London at night, with white-out copy in capital letters, set against them.
One execution runs with the copy: "Don't like what you smell when you walk past a homeless person? Perhaps it's because you've got your head up your arse."
Another states: "Sick and tired of people sleeping rough in your area? I shouldn't worry, their average life expectancy is only 42."
A third runs with the lines, "A community can only overlook a pregnant, 15-year-old in a doorway for so long. Generally until it discovers she's having a negative effect on property prices."
The first execution, which will run in The Big Issue magazine, is helping to illustrate the charity's "lethal streets" initiative. The advertising will also run in titles including GQ, Loaded, Dazed & Confused and Flux.
The ads were written by James Sinclair and art directed by Ed Morris.
They were shot by Nadav Kander.
The Big Issue Foundation offers support for people with addiction, mental illness, re-employment and accommodation problems.