The charity has shortlisted three roster shops to pitch for the business. Its in-house marketing team is handling the process.
The successful agency will be responsible for producing a digital ad campaign aimed at encouraging more people to sign up to the minimum £2 per week donation scheme. The brief will also include online media planning elements.
Cancer Research UK has traditionally invested heavily in direct marketing, but has recently shifted its focus towards digital communications using a roster of digital shops, including Agency Republic and OgilvyOne, to handle individual briefs.
A recent campaign by OgilvyOne used banner ads showing a live webcam feed of Dartmoor to show how new smoking legislation would make indoor spaces healthier.
In September, the digital agency Steel was appointed to a website design brief for the charity's annual "TacheBack" campaign.