The social networking site, founded just six years ago, has leapfrogged Yahoo! to become the biggest publisher of display ads, serving 176.3bn banners to US users in the first quarter of 2010.
This is just the beginning for 26-year-old Zuckerberg, who has grown Facebook's active user base to more than 400m worldwide. He has his sights set on ousting Google and establishing Facebook at the centre of the online experience for users and the advertisers vying to reach them.
In the past month alone, the social network has rolled out various commercial features including its 'Like' button, enabling users to share third-party content, and location-based status updates.
As we explain on page 6, tweaks to Facebook's terms and conditions mean that unless users opt out, their personal details will be made available to more than just other social networkers. Understandably, users aren't too keen to share their birthdays, religious views and family details with all and sundry - never mind those party photos.
Despite attempts to play down the backlash from bloggers, journalists and the European Commission, the emergency meeting held at Facebook's San Francisco HQ gives a clear indication of the severity of the problem.
Calls for users to commit 'Facebook suicide' threaten to undermine public trust in the site. Unless Zuckerberg nips the problem in the bud, his scheme for web domination could be foiled.