The exclusive covers have been revealed in a social media campaign staggered over 24 hours, ahead of the release of 'X-Men: Days of Future Past' later in the year.
The exclusive covers also feature the actor Sir Patrick Stewart, who portrays the series' Professor Xavier, and Bryan Singer, the director of the film.
The commemorative covers start a year of activity around Empire's 25th anniversary.
Mark Dinning, the editor-in-chief of Empire, said: "Over the next 12 months we will deliver a succession of the biggest exclusives in this brand's already illustrious history, working with the biggest names in Hollywood to bring film fans the world over some genuine movie events.
"We have always seen the job of Empire as bringing together the people who make the movies and the people who watch them, and this year we are going to go even bigger and better than ever before."