Executive creative directors Colin Lamberton and Seyoan Vela take on leadership responsibilities to head up Grey Amsterdam, reporting directly to Carolyn Carter, Grey Group EMEA CEO.
Lamberton and Vela, who co-founded St Luke's, joined Grey's EMEA team in London in 2007.
They provided the creative work behind two regional wins, Toshiba and Fortis.
In May 2008 they moved with the Fortis win to Amsterdam as executive creative directors to rebuild the agency as a creative resource for Grey's local and multinational clients.
Carter said: "As an international city with an extraordinary talent resource, Amsterdam is a perfect market for this kind of agency.
"From here the team offers international clients regional and global solutions without a creative bias associated with a particular market."
Klicks moves to a new role as business director EMEA and member of the Grey EMEA executive committee.
Reporting directly to Carter, he will contribute to new and existing clients across the region as well as the development of the network.
Lamberton said: "We believe clients like to work closely with creatives and strategic planners who are integrally involved in the brand from the ground up.
"Our approach is pragmatic -- in allowing for more discipline but less process we're removing unnecessary layers which clients shouldn't be expected to pay for.
"We're freeing up space for creativity in any form throughout the process, which is more in sync with what clients are calling for."