Anthea Turner will be the new face of The Health Lottery in a campaign promoting the live-draw show, which will increase to five episodes per week on Channel 5 at 9.55pm.
Turner will also feature in a brand campaign, "everybody wins", in September.
The move follows proposed changes to The National Lottery, which will see an additional ten balls added to the draw beginning from October. The Health Lottery has claimed that its players are seven times more likely to win.
In 2012, The Health Lottery appointed McCann Manchester to help grow the brand. The agency created TV and press activity with the strapline: "Share the love."
MediaCom was chosen to handle The Health Lottery’s media account in 2013.
Robert Campbell, the founder and creative director at Beta, said: "We’re really pleased to have the chance to work on a brand that has so much that is positive about it but which has been a bit shy about saying it."
The Health Lottery was established in 2011.