The ad aims to highlight the difficulties faced by people with dyslexia and to challenge people to sign up for the charity's revamped distance-learning courses, which it launched last autumn.
The type-only ad uses jumbled-up words to explain that it doesn't matter what order letters are in in a word, as long as the first and last are in the correct position. It becomes a call to action asking if the reader could help unjumble the letters for someone who can't.
It will run in London and breaks in the Evening Standard on 5 April.
The ad was written by Paul Hodgkinson and art directed by Bill Gallacher and Justin Shill. The typographer was Simon Warden.
Media planning and buying was handled by M&C Saatchi.