The agency, which has held Campbell's US media planning and buying since 1999, will take on media duties in five key European markets, across Asia and in Mexico.
However, the consolidation does not affect the £10 million UK account, which will remain with ZenithOptimedia. OMD will continue to handle Campbell's business in Canada.
Mediaedge:cia will add markets including Belgium, France, Germany, Sweden, Australia and China to its existing relationships in the US, Russia, Hong Kong, Malaysia, New Zealand, Puerto Rico, Singapore and Guatemala.
Colleen Milway, the global media director at Campbell's, said: "Our decision to consolidate planning and buying with the MEC global network was driven by our desire to improve the effectiveness and efficiency of our media spending globally."
Milway added that Campbell's is looking at "the increased potential for global media deals with our top media suppliers".