The launch of frontpage ads on the New York Times follows trials of ads on some of the frontpages of other sections of the paper.
Denise Warren, senior vice president and chief advertising officer for The New York Times Media Group, said: "This high impact placement represents an exciting new opportunity for our advertisers to reach our educated, affluent and influential readers across the country.
"In 2006 we began testing ads on some section fronts and received a very positive response from the advertising community.
"A strip ad on the front page of The New York Times will be highly attractive to advertisers looking for premium real estate for their campaigns."
The International Herald Tribune, which is owned by The New York Times Media Group, also offers front-page ad placements.