The publisher claimed four awards in total at the event which included best business website for XpertHR.co.uk, best online community for business-to-business site Farmers Weekly Interactive, and best online business ad sales team for RBI e-Newsletters.
IPC Media also had a good night, taking home three awards for best cross-media project, best research and insight project and best consumer editorial team for nme.com.
The Financial Times and BSkyB each picked up the third most awards. BSkyB won two gongs for best online consumer publisher and best consumer website for Sky News. The FT won best innovation for Mocking Bird Model and best use of video for FT.com.
Ruth Brownlee, the outgoing director of AOP, said: "This year's winners have produced work that shows real creativity, smart use of technology and commercial acumen."
The awards, which were held at London's Hilton Park Lane, have been running since 2002.
The AOP also announced yesterday at its annual conference that it would split its chairman's role in two. Outgoing chairman Simon Waldman, group director of digital strategy and development at Guardian Media Group, handed over his duties to Alison Reay, digital media director at Telegraph Media Group, and Mike Seery, chief information officer at The Economist.
The full list of winners:
Winner: Guardian News and Media - guardian.co.uk/katine
Editorial Team - Business
Winner: Incisive Media - Accountancy Age
Editorial Team - Consumer 2008
Winner: IPC Media - nme.com
Research & Insights Project 2008
Winner: IPC Media - The Origin Panel - Women's Space
Online Advertising Sales Team - Consumer 2008
Winner: Future Publishing PLC - Future Publishing - Digital Agency Team
Online Advertising Sales Team - Business 2008
Winner: Reed Business Information - RBI e-Newsletters
Winner: Financial Times - Mockingbird Model
Cross-Media Project 2008
Winner: IPC Media - The WKD Nuts Football Awards
Winner: Channel 4 - Ford Bite
Use of Video 2008
Winner: Financial Times - FT.com
Mobile Site 2008
Winner: News Group Newspapers - Sun Mobile
Online Community 2008
Winner: Reed Business Information - Farmers Weekly Interactive
Website 2008 - Business
Winner: Reed Business Information - XpertHR.co.uk
Website 2008 - Consumer
Winner: BskyB - Sky News
Online Publisher 2008 - Business
Winner: Reed Business Information - Reed Business Information
Online Publisher 2008 - Consumer