As official club sponsor, the Samsung logo will appear on the front of the League One club's home shirt and on the reverse of the away shirt.
However, the east London team has also brought in two other brands to appear on its kit, replacing this season's sponsor PartyGaming (which highlights its PartyPoker.com and PartyCasino.com brands).
Computer games publisher EA Sports will feature on the back of the home shirt and the front of the away shirt.
Online football store Pro-Direct Soccer will feature on the shorts of both kits.
The partnership is Samsung's third shirt sponsorship deal, alongside the commercial packages in place with Premier League Chelsea FC and League Two side Swindon Town FC.
Andy Griffiths, managing director of Samsung UK and Ireland, said: "We are delighted to add Leyton Orient to our football sponsorships in the UK.
"Samsung is committed to supporting football at every level in this country. We believe that the game can only flourish if the grassroots are properly nurtured."
Barry Hearn, chairman of Leyton Orient, said: "We are thrilled to welcome Samsung Electronics as our club sponsors for the 2012/13 season.
"We're really looking forward to working with them during what we are confident will be a successful season for the club."