Robert Saville, a founding partner at Mother, confirmed that Studzinski was joining the agency, but said his exact role was yet to be decided .
Sources within Publicis say that Studzinksi was becoming increasingly unhappy with his role, and was becoming disillusioned with the pressures of running the creative department of a network agency.
"He basically wants to sit in an office and create ads, which is where his major skills lie. He'll be great at Mother," one source said.
Studzinski is the third high-profile executive to depart Publicis since the arrival of Neil Simpson, the agency's chief executive, in September 2006. Simpson is in the process of making sweeping changes to the agency's senior management team.
In November last year, Kim Douglas, the Publicis executive planning director, left without a job to go to. In January, Mark Cramphorn, the chief operating officer, quit to join Tim Lindsay, the former Publicis chairman, at TBWA.
Studzinski said: "I've enjoyed my time at Publicis. I feel lucky to have spent the past four years working with some talented people and being part of the team producing work that we can all be proud of."
Studzinski joined Publicis in June 2003 from Saatchi & Saatchi, where he was head of art. He replaced Gerry Moira, who was promoted to the role of chairman.
Dave Droga, the Publicis worldwide creative director at the time, brokered the move after working with Studzinski at Saatchis.
Studzinski, who has won a variety of industry awards, started hsi career at Saatchis in 1991. He stayed there until 1999, when he left to join Bartle Bogle Hegarty. After less than a year, he came back to Saatchis as head of art.
His switch to Publicis came less than a month after a departmental restructure by the then Saatchis executive creative director, Tony Granger, in which Studzinski's title as head of art was scrapped.