The brand, owned by ZPG, whose other brands include Zoopla, Money and PrimeLocation, reached a deal with ITV and production companies Syco Entertainment and FremantleMedia.
Last year, the show achieved an average audience of 9.5 million viewers, with a peak of almost 13 million.
The sponsorship will involve new creative, created by the brand's ad agency Brothers & Sisters, aimed at "inspiring and motivating consumers to switch and save money off their household bills".
Gareth Helm, chief marketing officer at ZPG, said: "This is an excellent opportunity for us to further build the uSwitch brand and help the nation understand how they can save hundreds of pounds a year off their household bills in a matter of a few minutes."
The news comes days after uSwitch rival Moneysupermarket dumped Mother, the agency behind its acclaimed campaigns of recent years, after disappointing earnings.