W&K said that it was appointed on the strength of chemistry and ideas sessions and will be responsible for the creation and development of the new Pirelli global campaign.
The agency added that winning the Pirelli account, which is understood to be worth in the region of £18m, marks its entry into a new market category and gives it the opportunity to continue its "tradition of creating groundbreaking advertising for iconic brands".
Pirelli account claims to be the world's fifth-largest tyre manufacturer in terms of turnover, with a network of around 10,000 distributors and retailers across 160 countries.
Lee Newman, managing director of W&K Amsterdam, said: "Pirelli is an iconic brand with a history of innovative marketing. It's a brand with charisma and a company with soul. We're excited about the opportunity to be their agency."
John Norman, executive creative director of W&K Amsterdam, said: "We are ecstatic to be partnering with the Pirelli brand. Their heritage of design and provocative style are a perfect match for W&K's creative approach."