The move comes just weeks after the Camden-based 2am merged with the Icelandic film company Saga Films. Winterbottom will join the roster of the production company, which boasts the likes of Richard Loncraine and Damien O'Donnell, the director of East is East.
The news marks Winterbottom's first foray into commercials following a spate of highly acclaimed British films, such as A Cock and Bull Story, which starred Steve Coogan. Another of his films, The Road to Guantanamo, was a docudrama about the plight of the three British prisoners who were captured by US forces in Afghanistan. His 2002 film In This World won a Bafta and a Golden Bear award, while 24 Hour Party People, also starring Steve Coogan as the Factory Records founder Tony Wilson, documents the music scene in Manchester from the late 70s to the early 90s.
Winterbottom, who is currently based in London, will assess script suitability on a "project-by-project" basis. In his first weeks at 2am Films, a number of scripts have been considered, although none have yet been given the go-ahead.
Amanda Martin, the joint managing director of 2am Films, said: "The current market is looking for a more diverse and eclectic mix of directors beyond those with a purely commercials background. You only need to look at the contrast between the films The Road to Guantanamo and A Cock and Bull Story to see how varied Winterbottom's visual styles can be."